Total Synthesis of (±)-Butyl Ester of Rosmarinic Acid |
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引用本文: | Long Jiang HUANG,De Quan YU? Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing .Total Synthesis of (±)-Butyl Ester of Rosmarinic Acid[J].中国化学快报,2005(6). |
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作者姓名: | Long Jiang HUANG De Quan YU? Institute of Materia Medica Chinese Academy of Medical Sciences &Peking Union Medical College Beijing |
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作者单位: | Long Jiang HUANG,De Quan YU? Institute of Materia Medica,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing 100050 |
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摘 要: | Rosmarinic acid, a well-known natural product firstly isolated from rosemary by Scarpati and Oriente in 19581, possesses various kinds of biological activities such as antioxidant2 and antibacterial3. Recently, the synthesis and biological activities of related compounds of rosmarinic acid have received much attention, such as 4, 4?′-O-di-β-D- glucopyranosyl rosmarinic acid4, methyl ester of rosmarinic acid5-6 and rabdosiin7. Butyl ester of rosmarinic acid 1 (Scheme 1) was isolated from Is…
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