Efficient synthesis of 5H-cyclopenta[c]quinoline derivatives via palladium-catalyzed domino reactions of o-alkynylhalobenzene with amine |
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Authors: | Luo Yong Pan Xiaolin Wu Jie |
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Institution: | Department of Chemistry, Fudan University, Shanghai, People's Republic of China. |
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Abstract: | A novel and efficient route for the synthesis of 5H-cyclopentac]quinoline derivatives via a palladium-catalyzed domino reaction of o-alkynylhalobenzene with amine is described. The starting materials are easily available, and the reaction proceeds smoothly with high efficiency, which shows broad scope with good functional group tolerance. |
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