Bisoxazolidine-catalyzed enantioselective alkynylation of aldehydes |
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| Authors: | Wolf Christian Liu Shuanglong |
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| Institution: | Department of Chemistry, Georgetown University, Washington, D.C. 20057, USA. cw27@georgetown.edu |
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| Abstract: | A C2-symmetric bisoxazolidine derived from aminoindanol has been successfully applied in the asymmetric alkynylation of aldehydes. The ligand is readily available, has a wide substrate scope, and catalyzes the formation of chiral propargylic alcohols with excellent yields and enantioselectivties. |
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