Bioimaging Based on Nucleic Acid Nanostructures |
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| Authors: | HAN Lin WANG Yuang TANG Wantao LIU Jianbing DING Baoquan |
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| Institution: | School of Materials Science and Engineering,Henan Institute of Advanced Technology,Zhengzhou University,Zhengzhou 450001,P.R.China;CAS Key Laboratory of Nanosystem and Hierarchical Fabrication,CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology,Beijing 100190,P.R.China;CAS Key Laboratory of Nanosystem and Hierarchical Fabrication,CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology,Beijing 100190,P.R.China |
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| Abstract: | Nucleic acid nanostructures with structural programmability, spatial addressability and excellent biocompatibility have drawn much attention in various biomedical applications, such as bioimaging, biosensing and drug delivery. In this review, we summarize the recent research progress in the field of bioimaging based on nucleic acid nanostructures with different imaging models, including fluorescent imaging(FI), magnetic resonance imaging(MRI), photoacoustic imaging(PAI) and positron emission tomography/computed tomography(PET/CT) imaging. We also discuss the remaining challenges and further opportunities involved in the bioimaging research based on nucleic acid nanostructures. |
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| Keywords: | Nucleic acid nanostructure DNA self-assembly Bioimaging Multimodal imaging |
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