Poly(4-vinylpyridinium)hydrogen sulfate: An efficient heterogeneous catalyst for the one-pot synthesis of polyhydroquinolines via unsymmetrical Hantzsch reaction in aqueous medium |
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| Affiliation: | 1. Department of Chemistry, National Institute of Technology, Warangal 506004, AP, India;2. Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA |
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| Abstract: | A facile and highly efficient protocol for the synthesis of polyhydroquinolines via Hantzsch multicomponent condensation of dimedone, aryl/heteryl aldehydes, ethylacetoacetate and ammonium acetate utilizing poly(4-vinylpyridinium)hydrogen sulfate as a catalyst in aqueous medium has been described. The method offers several advantages such as high yield, short reaction time, simple workup, easy separation of the catalyst and its reusability. |
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| Keywords: | Aqueous medium Hantzsch reaction Polyhydroquinolines Poly(4-vinylpyridinium)hydrogen sulfate |
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