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Advanced Nanomaterials for Multimodal Molecular Imaging
Authors:YUAN Hui  LIANG Hanyu  HOU Peidong  LI Juan
Institution:The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital),Institute of Basic Medicine and Cancer(IBMC),Chinese Academy of Sciences,Hangzhou 310022,P.R.China;Key Laboratory for Analytical Science of Food Safety and Biology of Ministry of Education,State Key Laboratory of Photocatalysis on Energy and Environment,College of Chemistry,Fuzhou University,Fuzhou 350002,P.R.China;The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital),Institute of Basic Medicine and Cancer(IBMC),Chinese Academy of Sciences,Hangzhou 310022,P.R.China;Key Laboratory for Analytical Science of Food Safety and Biology of Ministry of Education,State Key Laboratory of Photocatalysis on Energy and Environment,College of Chemistry,Fuzhou University,Fuzhou 350002,P.R.China
Abstract:The development of multimodal molecular imaging contrast agents based on versatile nanomaterials has recently attracted much attention in disease diagnosis and therapeutic delivery. Contrast agents made from nanoparticles and used for multimodal imaging in vivo provide a multidimensional pathophysiological overview of diseases. This review summarizes recently developed advanced nanomaterials for multimodal molecular imaging. We comprehensively discuss these nanoparticle contrast agents in terms of their targeting modalities, limitations in clinical translation and future directions.
Keywords:Molecular imaging  Nanoparticle contrast agent  Multimodal imaging  In vivo imaging  Biomedicine  
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