| 金催化的炔烃羟基化反应: 合成2取代苯并呋喃化合物 |
| |
| 引用本文： | 张元,辛志君,薛吉军,李瀛.金催化的炔烃羟基化反应: 合成2取代苯并呋喃化合物[J].中国化学,2008,26(8):1461-1464. |
| |
| 作者姓名： | 张元 辛志君 薛吉军 李瀛 |
| |
| 作者单位： | 兰州大学化学化工学院，功能有机分子化学国家重点实验室，兰州 730000 |
| |
| 摘 要： | 本文报道了一种以邻炔基苯酚为原料，通过金催化的炔烃羟基化反应合成2取代苯并呋喃的方法. 该方法可以在温和的条件下快速以高产率得到各种2取代苯并呋喃. 关键前体邻炔基苯酚可以很容易由Sonogashira 反应制备.
|
| 关 键 词： | 苯并呋喃 金催化 炔烃羟基化 偶联 |
| 收稿时间： | 2008-1-8 |
| 修稿时间： | 2008-2-19 |
Gold‐catalyzed Alkyne Hydroxylation: Synthesis of 2‐Substituted Benzo[b]furan Compounds |
| |
| Yuan ZHANG,Zhi‐Jun XIN,Ji‐Jun XUE,Ying LI.Gold‐catalyzed Alkyne Hydroxylation: Synthesis of 2‐Substituted Benzo[b]furan Compounds[J].Chinese Journal of Chemistry,2008,26(8):1461-1464. |
| |
| Authors: | Yuan ZHANG Zhi‐Jun XIN Ji‐Jun XUE Ying LI |
| |
| Institution: | 1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China;2. Tel.: 0086‐0931‐8913103 (Y. Li);3. Fax: 0086‐0931‐8913103 (Y. Li) |
| |
| Abstract: | A strategy concerning the synthesis of 2‐substituted benzob]furan compounds from o‐alkynyl phenols via a gold‐catalyzed alkyne hydroxylation is described, which allows the rapid synthesis of various 2‐substituted benzob]furan derivatives in excellent yields under mild conditions. The o‐alkynyl phenol precursors were readily prepared with a Sonogashira coupling reaction. |
| |
| Keywords: | benzo[b]furan gold‐catalysis alkyne hydroxylation coupling |
|
| 点击此处可从《中国化学》浏览原始摘要信息 |
| 点击此处可从《中国化学》下载免费的PDF全文 |
