首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Ru-catalyzed asymmetric hydrogenation of alpha-phthalimide ketones and 1,3-diaryl diketones using 4,4'-substituted BINAPs
Authors:Hu Aiguo  Lin Wenbin
Institution:Department of Chemistry, CB 3290, University of North Carolina, Chapel Hill, NC 27599, USA.
Abstract:reaction: see text] A family of tunable precatalysts NH2Et2]{Ru(4,4'-BINAP)Cl}2(mu-Cl)3] was synthesized and used for highly enantioselective hydrogenation of phthalimide-protected amino ketones and 1,3-diaryldiketones. The bulky groups on the 4,4'-positions of BINAP were believed to be responsible for the enhancement of enantioselectivity (and diasteroselectivity) in these reactions.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号