Influence of Bovine Bone Content on In Vitro Degradation of Poly-L-lactic Acid and Bovine Bone Composite Materials |
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| Authors: | Z. H. Zhou Q. F. Yi L. H. Liu Y. M. Zhao X. P. Liu J. N. Zhou |
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| Affiliation: | 1. Key Laboratory of Theoretical Chemistry and Molecular Simulation of Ministry of Education, School of Chemistry and Chemical Engineering , Hunan University of Science and Technology , Xiangtan, P. R. China;2. State Key Laboratory for Powder Metallurgy , Central-South University , Changsha, P. R. China;3. Key Laboratory of Theoretical Chemistry and Molecular Simulation of Ministry of Education, School of Chemistry and Chemical Engineering , Hunan University of Science and Technology , Xiangtan, P. R. China |
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| Abstract: | In vitro degradation experiments of poly-L-lactic acid (PLLA) and bovine bone (BB) composites were carried out in a phosphate-buffered solution (PBS) at 37°C with a pH of 7.4. The influence of BB content on pH value of PBS, water uptake, molecular weights, molecular weight distributions, weight losses, mechanical strengths, and morphologies of PLLA/BB was investigated with degradation times. The results indicated that the presence of the BB modified the degradation of the PLLA matrix. The degradation rate of PLLA in the PLLA/BB composite was slower than the degradation rate of the sole PLLA material. Furthermore, the degradation rate of the composites became slower with the increasing content of BB in PLLA/BB composites. |
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| Keywords: | bovine bone composite content degradation in vitro poly-L-lactic acid |
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