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Stereoselective construction of fluorinated indanone derivatives via a triple cascade Lewis acid-catalyzed reaction
Authors:Cui Han-Feng  Dong Ke-Yan  Zhang Guang-Wu  Wang Lian  Ma Jun-An
Affiliation:Department of Chemistry, Tianjin University, Tianjin, 300072, China.
Abstract:A one-pot three-component cascade reaction proceeds by way of a Lewis acid-catalyzed Knoevenagel condensation/Nazarov cyclization/electrophilic fluorination sequence to afford fluorinated 1-indanone derivatives in moderate to good yields with high diastereoselectivities.
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