Stereoselective construction of fluorinated indanone derivatives via a triple cascade Lewis acid-catalyzed reaction |
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Authors: | Cui Han-Feng Dong Ke-Yan Zhang Guang-Wu Wang Lian Ma Jun-An |
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Affiliation: | Department of Chemistry, Tianjin University, Tianjin, 300072, China. |
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Abstract: | A one-pot three-component cascade reaction proceeds by way of a Lewis acid-catalyzed Knoevenagel condensation/Nazarov cyclization/electrophilic fluorination sequence to afford fluorinated 1-indanone derivatives in moderate to good yields with high diastereoselectivities. |
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