Fujiwara–Moritani Reaction of Weinreb Amides using a Ruthenium‐Catalyzed C−H Functionalization Reaction |
| |
| Authors: | Riki Das Dr Manmohan Kapur |
| |
| Institution: | Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Academic Building?II, Bhopal, India |
| |
| Abstract: | The ruthenium‐catalyzed Fujiwara–Moritani reaction (oxidative‐Heck reaction) of Weinreb amides is reported herein. The reaction affords exclusively ortho‐C?H olefination products, has excellent substrate scope and tolerates halogen functionalities, which increase the synthetic utility of the method. A variety of activated olefins as well as styrenes can be employed as coupling partners. |
| |
| Keywords: | amides C− H functionalization Fujiwara– Moritani oxidative Heck ruthenium |
|
