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The interaction mechanisms between Saccharomyces cerevisiae and menadione and its application in toxicology study
Authors:Zhao Jinsheng  Wang Zhong  Wang Min  Wang Huaisheng  He Qingpeng  Zhang He
Affiliation:

aDepartment of Chemistry and Chemical Engineering, Liaocheng University, 252059 Liaocheng, PR China

bSchool of Medicine, Ehime University, 791-0295 Toon, Japan

Abstract:This study describes interaction mechanism between menadione and the yeast with the aid of the catabolite assay and the culture fluorescence method, with a view towards exploitting the potential of the mediator in toxicology study. Double mediator system containing menadione and the hydrophilic mediator, ferricyanide, was employed for evaluating the toxic effects of furfural on the yeast and the results showed the well consistence between the MICREDOX method and the conventional method.
Keywords:Double mediator system   Menadione   Saccharomyces cerevisiae   Toxicology
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