The hematopoietic factor GM-CSF (Granulocyte-macrophage colony-stimulating factor) promotes neuronal differentiation of adult neural stem cells in vitro |
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| Authors: | Carola Krüger Rico Laage Claudia Pitzer Wolf-Rüdiger Schäbitz Armin Schneider |
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| Institution: | (1) Sygnis Bioscience, Im Neuenheimer Feld 515, 69120 Heidelberg, Germany;(2) Department of Neurology, University of Mnster, Albert-Schweitzer-Str.33, 48149 Mnster, Germany |
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| Abstract: | Background Granulocyte-macrophage colony stimulating factor (GM-CSF) is a hematopoietic growth factor involved in the generation of granulocytes,
macrophages, and dendritic cells from hematopoietic progenitor cells. We have recently demonstrated that GM-CSF has anti-apoptotic
functions on neurons, and is neuroprotective in animal stroke models. |
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