Chiral Separation of Ibuprofen and Terbutaline by Nonaqueous Capillary Electrophoresis with Conductance Detection |
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Authors: | DENG Guang-hui WEI Shou-lian MO Jin-yuan |
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Institution: | 1. Department of Chemistry, Guangxi University for Nationalities, Nanning 530006, P. R. China;
2. Department of Chemistry, Zhongshan University, Guangzhou 510275, P. R. China |
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Abstract: | In the nonaqueous N,N-dimethylformamide medium, the chiral drugs ibuprofen and terbutaline were successfully separated with sulfonyl-β-cyclodextrin(s-β-CD) as the chiral selector by capillary electrophoresis with conductance detection. The comparison of the effects of three CDS(β-CD, diethylic-β-CD, sulfonyl-β-CD) on the chiral separation was made and the resolution mechanism was proposed. |
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Keywords: | Nonaqueous medium Capillary electrophoresis with conductance detection Resolution N N-Dimethylformamide |
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