|
|||||
|
|
Total synthesis of amphidinolide E |
|
| Authors: | Va Porino Roush William R |
| Institution: | Department of Chemistry, Scripps Florida, Jupiter, Florida 33458, USA. |
| Abstract: | A convergent and highly stereocontrolled synthesis of amphidinolide E (1) has been accomplished. The synthesis features a highly diastereoselective (>20:1) BF3.Et2O promoted 3+2] annulation reaction between aldehyde 3 and allylsilane 4 to afford substituted tetrahydrofuran 2. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |