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Efficient Prins cyclization in environmentally benign method using ion exchange resin catalyst |
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| Abstract: | Abstract Amberlyst-15® (H+) resin catalyzes efficient one-pot solvent free Prins cyclization of an aldehyde and a homoallylic alcohol to yield dihydropyrans and 4-hydroxytetrahydropyrans. The products, which display interesting olfactory property, are obtained under mild condition and by simple work up. The recovered resin can be used repeatedly . |
| Keywords: | dihydropyrans 4-hydroxytetrahydropyrans Amberlyst-15® Prins cyclization olfactory property |