A green development of Bernthsen 9-substituted acridine synthesis in the absence of solvent catalyzed by p-toluenesulphonic acid (p-TSA)

Abstract

Bernthsen reaction has been carried out under microwave irradiation in the presence of p-TSA (10 mol%) as catalyst in a solventless reaction to provide 9-substituted acridines. In the present report, time economy and better yields as compared to conventional Bernthsen reaction are described.