Abstract: | Abstract Crossed aldol condensation of aromatic aldehydes with cyclic ketones in the presence of catalytic amount of NH4H2PO4/SiO2 (as a safe, green, and cheap heterogeneous catalyst) under solvent-free condition afforded α,?-bis(substituted-benzylidene) cycloalkanones in high yields. This method is general with respect to all types of aromatic aldehydes and is an eco-friendly procedure. And the catalyst is easily prepared, stable, reusable, and efficient under the reaction conditions. |