Polyethylene glycol (PEG) mediated green synthesis of 2,5-disubstituted 1,3,4-oxadiazoles catalyzed by ceric ammonium nitrate (CAN)

Abstract

Ceric ammonium nitrate in polyethylene glycol has been used as a sustainable, non-volatile, and ecofriendly catalytic medium for the green synthesis of 2,5-disubstituted 1,3,4-oxadiazoles. This protocol is effective toward various substrates having different functionalities. The easy recyclability of the reaction medium makes the reaction economically and potentially viable for commercial applications.