A new synthesis of N-alkyl 4-methyl-1,4-dihydropyridines utilizing sec-aminodienyl esters with crotonaldehyde |
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Authors: | Koike T |
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Affiliation: | Showa Pharmaceutical University, Machida, Tokyo, Japan. koike@ac.shoyaku.ac.jp |
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Abstract: | The reactions of sec-aminodienyl esters 3 with crotonaldehyde (4) afforded N-alkyl 3-[2-(methoxycarbonyl)ethenyl]-4-methyl-1,4-dihydropyridines 5, providing a new azaelectrocyclization reaction. |
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