| 基于SPR生物传感器的抗菌中药药效评价方法研究 |
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| 引用本文： | 张鹤林,张国龙,张康,汪灿华.基于SPR生物传感器的抗菌中药药效评价方法研究[J].电子器件,2015,38(1). |
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| 作者姓名： | 张鹤林 张国龙 张康 汪灿华 |
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| 作者单位： | 江西中医药大学计算机学院,南昌,330004 |
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| 基金项目： | 江西省卫生厅中医药科研项目，江西中医药大学重点学科项目 |
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| 摘 要： | 目的：为抗菌中药药效进行实时检测，对药效评价给出定量分析。方法系采用真空热蒸镀法镀金属银膜制作出一种光纤SPR生物传感器，感测抗菌中药作用过程中抗原与抗体各个参数变化，为药效评价提供数据依据。该传感器的应用具有快速、客观、准确、高效的实时检测功能，为抗菌中药药效定量评价提供了依据。光纤SPR生物传感器的应用为抗菌中药药效评价给出了定量依据，有望最终用于指导临床准确应用抗菌中药。
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| 关 键 词： | SPR生物传感器 中药 真空热蒸镀法 药效评价 |
Research on efficacy evaluation methods of antibacterial Chinese medicine Base on SPR biosensor |
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| ZHANG Helin,ZHANG Guolong,ZHANG Kang,WANG Canhua?.Research on efficacy evaluation methods of antibacterial Chinese medicine Base on SPR biosensor[J].Journal of Electron Devices,2015,38(1). |
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| Authors: | ZHANG Helin ZHANG Guolong ZHANG Kang WANG Canhua? |
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| Abstract: | Objective to antibacterial effect of traditional Chinese medicine for real-time detection, analysis of quantitative efficacy evaluation. Methods the vacuum thermal evaporation plating layer metal film produced fiber SPR sensor, sensing changes in antimicrobial antigen and antibody of each parameter in the process of Chinese medicine, provide the data basis for efficacy evaluation. The results of real-time detection function, objective, accurate, fast and efficient application of the sensor, provides the basis for the evaluation of the antibacterial effect of traditional Chinese medicine quantitative. Conclusion the application of fiber-optic SPR biosensor for antibacterial efficacy evaluation of traditional Chinese medicine is a quantitative basis. Potentially used in guiding the clinical application of traditional Chinese medicine and Chinese medicine accurate evaluation and selection. |
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| Keywords: | SPR biosensor traditional Chinese medicine vacuum thermal evaporation method efficacy evaluation |
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