Syntheses of Aromatic Aldehydes by Laccase of Pleurotus ostreatus MTCC-1801 |
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Authors: | Pankaj Kumar Chaurasia Sudha Yadava Sunil Kumar Singh |
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Institution: | Department of Chemistry , D.D.U. Gorakhpur University , Gorakhpur , Uttar Pradesh , India |
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Abstract: | Selective bioconversion of the aromatic methyl group to its aldehyde group is one of the best applications of the laccases. In the present communication, crude laccase, obtained from the liquid culture medium of the fungal strain Pleurotus ostreatus MTCC-1801, has been used for the selective bioconversion of toluene, 3-nitrotoluene, 4-nitrotoluene, 2-fluorotoluene, 4-fluorotoluene, 2-chlorotoluene, 3-chlorotoluene, 4-chlorotoluene, and 3,4-dimethoxytoluene to benzaldehyde, 3-nitrobenzaldehyde, 4-nitrobenzaldehyde, 2-fluorobenzaldehyde, 4-fluorobenzaldehyde, 2-chlorobenzaldehyde, 3-chlorobenzaldehyde, 4-chlorobenzaldehyde, and 3,4-dimethoxybenzaldehyde, respectively, in the presence of 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS) as a mediator molecule. Time taken by these conversions was 1–2 h, and average yield of products was more than 93%. |
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Keywords: | ABTS HPLC laccase Pleurotus ostreatus selective oxidation |
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