Efficient Synthesis of Substituted Indene Derivatives |
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| Authors: | Sonia Taktouk Jihène Ben Kraiem |
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| Institution: | Laboratory of Selective Organic Synthesis and Biological Activity, Faculty of Science , El Manar University , Tunis , Tunisia |
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| Abstract: | An efficient protocol for the synthesis of new functionalized indenes 3 was successfully realized. Thus the coupling reaction of allyl acetate 2 with Grignard reagents in the presence of a catalytic amount of LiCuBr2 at low temperature afforded pure ethyl 1-alkyl-1H-indenes-2-carboxylate 3 in good yields. |
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| Keywords: | Allylic acetates ethyl 1-alkyl-1H-indenes-2-carboxylate Grignard reagents indenols |
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