Synthetic Strategies for Fused Benzothiazoles: Past,Present, and Future |
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Authors: | Manoj N Bhoi Mayuri A Borad |
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Institution: | Department of Chemistry, School of Sciences , Gujarat University , Ahmedabad , India |
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Abstract: | Benzothiazole is used as a building block in organic synthesis, which serves as a key template for the development of various therapeutic agents and shows a wide spectrum of activities. The attractive application of benzothiazole in organic synthesis is undoubtedly due to the highly reactive C-2 amino group, which is responsible for the change in its bioactivity. The construction of a poly-heterocyclic compound with the fused hetero-systems has attracted increasing attention because of the diverse range of potential therapeutic activities. Significant efforts have been undertaken to exploit different synthetic routes to these compounds. This article gives a comprehensive account of the synthetic utility of benzothiazole employed in the design and synthesis of different types of compounds containing fused heterocyclic rings with greater emphasis on recent literature. |
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Keywords: | 2-Amino benzothiazole benzothiazole fused heterocyclic compound multicomponent reactions (MCR) thiazole derivative |
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