Unusual Course of the Reaction of Allyl Phosphine Oxides with the Grundmann Ketone |
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Authors: | Katarzyna Sokolowska |
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Affiliation: | Department of Chemistry , University of Warsaw , Warsaw , Poland |
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Abstract: | This article describes efficient preparation of isomeric allyl phosphine oxides possessing a protected cyclohexanediol fragment. Their base-catalyzed interconversions are examined and reactions with the Grundmann ketone provide an adduct containing the rearranged vinyl phosphine oxide moiety, instead of 19-norvitamin D3 analogs, the expected products of the Horner–Wittig process. |
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Keywords: | Allyl phosphine oxide Grundmann ketone vinyl phosphine oxide |
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