1. Department of Science and Humanities , Bandwan Polytechnic , Purulia , West Bengal , India;2. Department of Chemistry , Indian Institute of Chemical Biology, Council of Scientific and Industrial Research , Kolkata , India
Abstract:
A high-yielding environmentally benign protocol has been developed for the synthesis of 3-(pyrrol-1-yl)-indolin-2-ones from the reaction of isatin and trans-4-hydroxy-L-proline in aqueous micellar medium. The method is operationally simple and more effective than the previous methods in terms of the yield of the products and the reaction time.