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Novel Route for the Synthesis of 3-(Pyrrol-1-yl)-indolin-2-ones in Aqueous Micellar Medium |
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| Authors: | Subhendu Naskar Swarbhanu Sarkar |
| Institution: | 1. Department of Science and Humanities , Bandwan Polytechnic , Purulia , West Bengal , India;2. Department of Chemistry , Indian Institute of Chemical Biology, Council of Scientific and Industrial Research , Kolkata , India |
| Abstract: | A high-yielding environmentally benign protocol has been developed for the synthesis of 3-(pyrrol-1-yl)-indolin-2-ones from the reaction of isatin and trans-4-hydroxy-L-proline in aqueous micellar medium. The method is operationally simple and more effective than the previous methods in terms of the yield of the products and the reaction time. |
| Keywords: | Isatin micelle 3-(pyrrol-1-yl)-indolin-2-ones reactions in water |