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An Improved Process for the Enantioselective Synthesis of HCV NS5A Inhibitor Elbasvir (MK-8742) Chiral Amine Intermediate |
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| Authors: | Chapala Vijaya Lakshmi Katari Naresh Kumar Malavattu Giri Prasad Kerru Nagaraju Reddy Pedavenkatagari Narayana Marisetti Vishnu Murthy |
| Institution: | 1.Department of Chemistry, School of Science, GITAM deemed to be University, Hyderabad, 502329, Telangana, India ;2.Department of Chemistry, GITAM School of Science, GITAM University, Bengaluru Campus, 561203, Karnataka, India ;3.Analytical Research and Development, ScieGen Pharmaceuticals Inc., Hauppauge, 11788, New York, USA ; |
| Abstract: | Russian Journal of General Chemistry - Large-scale enantioselective synthesis of the chiral amine unit of HCV NS5A inhibitor Elbasvir has been accomplished in six steps, with 55% overall yield. The... |
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