Synthesis of 2-arylbenzo[b]furans via copper(I)-catalyzed coupling of o-iodophenols and aryl acetylenes |
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Authors: | Bates Craig G Saejueng Pranorm Murphy Jaclyn M Venkataraman D |
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Institution: | Department of Chemistry, University of Massachusetts-Amherst, 710 North Pleasant Street, Amherst, Massachusetts 01003, USA. |
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Abstract: | reaction: see text] We report a copper(I)-catalyzed procedure for the synthesis of 2-arylbenzob]furans. This protocol can be used to synthesize a variety of 2-arylbenzob]furans in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives, and is palladium-free. |
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