Sensing colorimetric approaches based on gold and silver nanoparticles aggregation: Chemical creativity behind the assay. A review |
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| Authors: | Diana VilelaAuthor Vitae,Marí a Cristina Gonzá lezAuthor VitaeAlberto Escarpa |
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| Affiliation: | Departamento de Química Analítica e Ingeniería Química, Facultad de Química, Edificio Polivalente, Universidad de Alcalá, Ctra. Madrid-Barcelona km 33,600, 28871 Alcalá de Henares, Madrid, Spain |
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| Abstract: | Localized surface plasmon resonance (LSPR) is one of the most remarkable features of gold nanoparticles (Au NPs) and silver nanoparticles (Ag NPs). Due to these inherent optical properties, colloidal solutions of Au and Ag NPs have high extinction coefficients and different colour in the visible region of the spectrum when they are well-spaced in comparison with when they are aggregated. Therefore, a well-designed chemical interaction between the analyte and NPs surroundings leads to a change of colour (red to blue for Au NPs and yellow to brown for Ag NPs from well-spaced to aggregated ones, respectively) allowing the visual detection of the target analyte. |
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| Keywords: | AA, Amino Acids Aden, Adenosine ALP, Alkaline Phosphatase ATP, Adenosine triphosphate CD, Ciclodextrin Ce, Crown Coc, Cocaine CIAP, Calf Intestine Alkaline Phosphatase Cys, Cysteine Cyst, Cysteamine DNA, Deoxyribonucleic acid ds, Double Stranded DSL, Dynamic Light Scattering dT, Deoxythymidylic DTC, Dithiocarbamate DAB, Diaminobenzenes EREs, Estrogen Response Elements Gluc, Glucose GOD, Glucose Oxidase HA, Hyaluronic acid His, Histidine HSA, Human serum albumin Hep, Heparin hERs, Human Estrogen Receptors ICP-MS, Inductively coupled plasma mass spectrometry LCD, Linear concentration dependence LOD, Limit of Detection Lysz, Lysozyme Mel, Melamine MTA, (11-mercapto-undecyl)-trimethyl ammonium Ngn3, Neurogenin3 Op, Optunal PCR, Polymerase chain reaction PKA, Protein kinase A p-NA, p-Nitroanilina poly-Tn, poly-Thyminen PRLS, Plasmon Resonance Light Scattering pSC6, p-sulfonatocalix SNPs, Single Nucleotide Polymorphisms ss, Single stranded TEM, Transmission electron microscopy Thr, Thrombin TNBS, 2, 4, 6-Trinitrobenzenesulfonic Tryp, Trypsin UCA, Uracil-5-carboxylic Acid FT-IR, Fourier transform infrared spectroscopy UV, Ultraviolet |
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