| Synthesis of （2R,4R）—2—N—tert—Butyloxycarbonyl Amino—4,5—epoxido—valeric Acid Methyl Ester |
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| 引用本文： | XinRongQIN YuLiXIE 等. Synthesis of （2R,4R）—2—N—tert—Butyloxycarbonyl Amino—4,5—epoxido—valeric Acid Methyl Ester[J]. 中国化学快报, 2002, 13(2): 111-112 |
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| 作者姓名： | XinRongQIN YuLiXIE 等 |
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| 作者单位： | [1]StateKeyLaboratoryofDrugResearch,ShanghaiInstituteofMateriaMedica,ShanghaiInsituteforBiologicalSciences,ChineseAcademyofSciences,Shanghai200031 [2]StateKeyLaboratoryofDrugResearch,ShanghaiInstituteofMate |
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| 摘 要： | The stereoselective synthesis of (2R,4R)-2-N-tert-butyloxycarbonyl amino-4,5-epoxido-valeric acid methyl ester 8,which is the key intermediate for the synthesis of (2′S,2R)-3-trans-nitrocyclopropyl-alanine,was first accomplished.
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| 关 键 词： | 合成 （2R，4R）－2－N－叔丁基氧化羰基氨基－4，5－环氧戊酸甲酯 手性化合物 |
Synthesis of (2R, 4R)-2-N-tert-Butyloxycarbonyl Amino-4,5-epoxido-valeric Acid Methyl Ester |
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| Xin Rong QIN,Yu Li XIE,Qiao Ling ZHANG,Hui Bing LUO,Yu Yuan XIE. Synthesis of (2R, 4R)-2-N-tert-Butyloxycarbonyl Amino-4,5-epoxido-valeric Acid Methyl Ester[J]. Chinese Chemical Letters, 2002, 13(2): 111-112 |
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| Authors: | Xin Rong QIN Yu Li XIE Qiao Ling ZHANG Hui Bing LUO Yu Yuan XIE |
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| Abstract: | The stereoselective synthesis of (2R, 4R)-2-N-tert-butyloxycarbonyl amino-4, 5-epoxido- valeric acid methyl ester 8, which is the key intermediate for the synthesis of (2S, 2R) -3-trans-nitrocyclopropyl-alanine, was first accomplished. |
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| Keywords: | Amino acid epoxide chiral. |
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