Functionalized ketones by iron mediated reaction of grignard reagents with acyl chlorides期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Functionalized ketones by iron mediated reaction of grignard reagents with acyl chlorides

Affiliation:	1. Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznań, Poland;2. AM2N, UMR 5253, ICGM, ENSCM, 8 Rue de l''Ecole Normale, 34296 Montpellier, Cedex 5, France;1. Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China;2. University of Chinese Academy of Sciences, Beijing 10049, China;1. Organic & Biomolecular Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500 607, India;2. Academy of Scientific and Innovative Research, India

Abstract:	The iron(III)-catalyzed cross-coupling reaction between Grignard reagents and acyl chlorides was found to be widely applicable to the synthesis of various functionalized ketones in good yields under mild conditions; the series of examples includes the synthesis of chiral methyl ketones and symmetric diketones.

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