Rapid and efficient synthesis of a fully functionalized synthon for the bottom half of the antiparasitic agent,ivermectin |
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| Affiliation: | 1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, PR China;2. Hainan Institute of Science and Technology, Haikou 571126, PR China;1. Seoul National University Hospital, Chongnogu, Seoul, Republic of Korea;2. Hanmaeum Changwon Hospital, Republic of Korea |
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| Abstract: | The preparation of the bottom half of ivermectin 3 in 10 steps and 9% overall yield is reported. |
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