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Selenium dioxide catalyzed oxidation of secondary amines with hydrogen peroxide. Simple synthesis of nitrones from secondary amines
Affiliation:1. Hubei Key Laboratory of Drug Synthesis and Optimization, Jingchu University of Technology, Hubei 448000, China;2. Department of Sciences, John Jay College and The Graduate Center, The City University of New York, New York, NY 10019, USA;1. Key Laboratory of Functional Inorganic Material Chemistry (Ministry of Education of China) and School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, PR China;2. School of Pharmacy, Jiamusi University, Jiamusi 154007, PR China
Abstract:Oxidation of secondary amines with hydrogen peroxide in the presence of selenium dioxide catalyst at room temperature gives nitrones, which are versatile synthetic intermediates, highly efficiently.
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