Stereospecific conjugate addition of organolithium reagents to naphthylimines. A facile route to 1,1,2- and 1,2-substituted dihydroronaphthalenes |
| |
| Affiliation: | 1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Hyderabad 500037, India;2. Department of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research, Hyderabad 500037, India;3. Indian Institute of Chemical Technology, Hyderabad 500607, India;1. Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan;2. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan |
| |
| Abstract: | Addition of organolithium reagents at low temperature to the cyclohexylimine of 1-naphthaldehyde followed by electrophilic trapping of the intermediate gives rise to high yields of the title compounds. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
