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Dietary Polyphenols: Extraction,Identification, Bioavailability,and Role for Prevention and Treatment of Colorectal and Prostate Cancers
Authors:Naveed Ahmad  Muhammad Qamar  Ye Yuan  Yasir Nazir  Polrat Wilairatana  Mohammad S. Mubarak
Abstract:Fruits, vegetables, and other edible plants in our diet have numerous health benefits, due to the bioactive compounds in these food items, including polyphenols. These plants are a rich and promising source of natural products and phytochemicals that can be used to treat and prevent numerous diseases and prevent the progression of cancer. Dietary polyphenols exhibit chemo-preventive and therapeutic effects against various ailments, including several types of cancer. The current study focuses on polyphenol’s traditional and advanced extraction methods, with supercritical extraction as a novel approach. It also deals with their identification, bioavailability, and role in preventing and treating colorectal and prostate cancers. Additionally, the article covers the literature that deals with the anticancer activities of polyphenols, as well as their potential use as anticancer agents.
Keywords:polyphenols   extraction technique   bioavailability   apoptosis   colorectal cancer   prostate cancer   cell viability   minimum half-inhibitory concentration
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