Novel antiparasitic agents derived by modification of a new natural product series |
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Affiliation: | 1. Department of Microbiological Chemistry, Glaxo Group Research, Greenford, Middlesex UB6 0HE, U.K.;2. Department of Chemistry, Imperial College of Science & Technology, South Kensington, London SW7 2AY, U.K. |
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Abstract: | Regioselective reactions on the C5-, C7- and C23-hydroxyl groups of the macrocyclic lactones (1), (3) and (4) are described. |
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