An iterative procedure for differential analysis of gene expression |
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Authors: | Avner Bar-Hen Stéphane Robin |
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Institution: | 1. Université Aix-Marseille III, FST Saint Jérôme, case 451, 13397 Marseille cedex 20, France;2. INA-PG/INRA Biométrie, 16, rue Claude Bernard, 75005 Paris, France |
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Abstract: | Microarrays are a popular technology to study genes that are differentially expressed between two conditions. In this Note, we propose an iterative procedure to determine the biggest subset of non-differentially expressed genes. We prove a pseudo Markov relationship that allows practical computations. We obtain explicit expressions for FDR and the level of the proposed test at each step. To cite this article: A. Bar-Hen, S. Robin, C. R. Acad. Sci. Paris, Ser. I 337 (2003). |
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