Determination of sulpha-drugs with ion-selective membrane electrodes |
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| Authors: | Ionescu M Cilianu S Bunaciu A A Coşofreţ V V |
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| Institution: | Institute of Chemical and Pharmaceutical Research Bucharest, 74351-Sos. Vitan 112, Bucharest-3, Romania. |
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| Abstract: | A liquid-membrane mercury(II)-sensitive electrode is used for determination of various sulpha drugs by addition of excess of mercuric nitrate and potentiometric back-titration of the surplus mercury(II) with EDTA. The performance of the electrode is compared with that of an Ag(2)S crystal-membrane electrode. Attempts to prepare a sulphamethoxazole-sensitive electrode failed. |
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