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Pd(l‐proline)2 complex: an efficient catalyst for Suzuki–Miyaura coupling reaction in neat water
Authors:Guofu Zhang  Yuxin Luan  Xingwang Han  Yong Wang  Xin Wen  Chengrong Ding
Affiliation:College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou, China
Abstract:An efficient catalytic system for Suzuki–Miyaura coupling reactions in neat water has been developed by using a water‐soluble Pd(l ‐proline)2 catalyst. Under the optimized conditions, various biaryl compounds were obtained in good to excellent yields and a wide range of functional groups on the tested substrates were well tolerated. The catalytic system could be reused at least six times with no significant loss in its activity. Copyright © 2014 John Wiley & Sons, Ltd.
Keywords:palladium  N,O‐ligand  Suzuki–  Miyaura reaction  biaryls  water
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