Investigation of Single‐Drug‐Encapsulating Liposomes using the Nano‐Impact Method |
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| Authors: | Dr Wei Cheng Prof?Dr Richard G Compton |
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| Institution: | Department of Chemistry, Physical & Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford, OX1 3QZ (UK) |
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| Abstract: | Encapsulating liposomes are widely used for controlled drug delivery. We report the use of nano‐impact experiments for the electrochemical attomolar quantification of the liposome load, uniquely at the single liposome level, using vitamin C encapsulated liposomes as a model. The size of the liposomes and their picomolar concentration are also determined in biological buffer in real time. |
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| Keywords: | drug delivery electrochemistry liposomes nano‐impact method nanoparticles |
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