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Ytterbium triflate catalysed Meerwein-Ponndorf-Verley (MPV) reduction
Authors:Adriano Mollica  Salvatore GenoveseFrancesco Pinnen  Azzurra StefanucciMassimo Curini  Francesco Epifano
Affiliation:a Dipartimento di Scienze del Farmaco, Università “G. D’Annunzio” di Chieti-Pescara, Via dei Vestini 31, 66100 Chieti Scalo (CH), Italy
b Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, Università degli Studi di Perugia, Via del Liceo 1, 06123 Perugia, Italy
Abstract:Ytterbium triflate was shown to be effective in promoting the reduction of substituted aromatic and aliphatic aldehydes and ketones using isopropanol as the solvent and the reducing agent. The whole process furnished the desired adducts in 22-98% yield.
Keywords:Carbonyl compounds   Heterogeneous catalysis   Meerwein-Ponndorf-Verley reaction   Reduction   Ytterbium triflate
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