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A novel method for the synthesis of 5-substituted 1H-tetrazole from oxime and sodium azide |
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| Authors: | Umakant B PatilKedar R Kumthekar Jayashree M Nagarkar |
| Institution: | Department of Chemistry, Institute of Chemical Technology (Deemed University), Nathalal Parekh Marg, Matunga(E), Mumbai 400 019, India |
| Abstract: | A simple and efficient protocol is developed for the synthesis of 5-substituted 1H-tetrazoles from various oximes and sodium azide (NaN3) by using copper acetate as a catalyst. |
| Keywords: | 5-Substituted 1H-tetrazole [3+2] Cycloaddition Oxime Cu(OAc)2 |
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