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Dysoxylentin A, the first 21-nortriterpenoid bearing a 2-(propan-2-ylidenyl)furan-3(2H)-one, from Dysoxylum lenticellatum |
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| Authors: | Ting Tang Shang-Gao Liao Zhi NaYan Li You-Kai Xu |
| Affiliation: | a Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla 666303, Yunnan, China b Guiyang Medical University, Guiyang 550004, Guizhou, China c State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China d Graduate University of Chinese Academy of Sciences, Beijing 100049, China |
| Abstract: | Dysoxylentin A (1), the first 21-nortriterpenoid bearing a 2-(propan-2-ylidenyl)furan-3(2H)-one functional group was isolated from the stem of Dysoxylum lenticellatum. Its structure was elucidated by extensive spectroscopic analysis. A plausible biosynthetic pathway was postulated. Dysoxylentin A exhibited selective cytotoxicity against HL-60 tumor cell line. |
| Keywords: | Dysoxylum lenticellatum Dysoxylentin A 21-Nortriterpenoid Cytotoxicity |
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