Abstract: | Two different convenient methods have been developed for the synthesis of condensed thieno2,3-b]pyridines. The intramolecular cyclization of 3-amino-2-hydrazinocarbonyl-7,7-dimethyl-7,8-dihydo-5H-pyrano3,4-e]-thieno2,3-b]pyridine was carried out to give 7,7-dimethyl-2-oxo-1,2,6,7-tetrahydro-9H-pyrano3′,4′-e]-imidazo4″,5″∶2,3]thieno5,4-b]pyridine, which is the first representative of a new heterocyclic system. |