'Nucleo-nanocages': designed ternary oligodeoxyribonucleotides spontaneously form nanosized DNA cages |
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Authors: | Matsuura Kazunori Yamashita Taro Igami Yuuko Kimizuka Nobuo |
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Institution: | Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan. |
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Abstract: | DNA three-way junctions formed from three 30-mer oligonucleotides that contain single-chained self-complementary sticky ends spontaneously self-assemble into 'nucleo-nanocages': the exo- and endo-nuclease digestion experiments indicate that defects such as the single and double strand end structures are absent on the spherical nano-assemblies, providing clear evidence for the closed nanocage structure. |
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