Binding of an inhibitor of the p53/MDM2 interaction to MDM2 |
| |
Authors: | Duncan Sara J Cooper Matthew A Williams Dudley H |
| |
Affiliation: | Dept of Chemistry, Lensfield Rd, Cambridge, UK CB2 1EW. |
| |
Abstract: | The mode of action of the secondary metabolite chlorofusin, which antagonises the interaction between p53 and MDM2, involves direct binding to the N-terminal domain of MDM2. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|