4-hydroxy-2-quinolones. 176*. 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. synthesis,physicochemical and biological properties |
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| Authors: | I. V. Ukrainets A. A. Davidenko E. V. Mospanova L. V. Sidorenko E. N. Svechnikova |
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| Affiliation: | (1) National University of Pharmacy, Kharkiv, 61002, Ukraine;(2) N. I. Pirogov Vinitsa National Medical University, Vinnitsa, 21018, Ukraine;(3) Chemical Technology Institute, V. Dal East-Ukrainian National University, Rubizhne, 93003, Ukraine |
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| Abstract: | We have carried out the synthesis and a comparative analysis of the acidic properties of a large group of 4-R-2-oxo-1,2-dihydroquinoline-3-carboxylic acids. Features of the recorded NMR spectra of these compounds are discussed together with their analgesic properties. |
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