Two new lanostane triterpenoids from Abies sachalinensis |
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Authors: | Hui Yuan Gao Jian Huang Bo Hang Sun Masonori Kuroyanagi Li Jun Wu |
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Affiliation: | [1]School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China [2]Faculty of Life and Environment School, Prefectural University of Hiroshima, Hiroshima 727-0023, Japan |
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Abstract: | The continuous chemical investigation on the ethyl acetate (EtOAc) soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton. They were identified as 3,4-seco-8-(14→,13R)abeo-17,13-friedo-9β-lanosta-4(28), 7,14(30),24-tetraen-26,23-olide-23-hydroxy-3-oic acid (1) and 7,14-mariesa-dien-3a-hydroxy-25-methoxy-26-oic acid (2). Structural determination of these compounds were carried out by the spectral studies especially by the two digital (2D)-NMR and high-resolution MS experiences. |
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Keywords: | Abies sachalinensis Rearranged lanostane 17,13-Friedolanostane |
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