Metabolites from sponges as inhibitors of β-1, 3-glucanase

The action of a number of aromatic and nitrogen heterocyclic metabolites from sponges on -1,3-glucanase Lo from the bivalve molluskChlamys albidus has been investigated. The greatest inhibiting action on the activity of -1,3-glucanase Lo was shown by puupehenone derivatives.Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Branch, Academy of Sciences of the USSR, Vladivostok. Translated from Khimiya Priorodnykh Soedinenii, No. 4, pp. 497–500, July–August, 1990.