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云南美登木内生真菌Phomopsis sp. Lz42的化学成分
引用本文:袁琳,马娟,王婷,李国红,沈月毛,赵沛基.云南美登木内生真菌Phomopsis sp. Lz42的化学成分[J].高等学校化学学报,2009,30(1):78-81.
作者姓名:袁琳  马娟  王婷  李国红  沈月毛  赵沛基
作者单位:1. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明,650204;中国科学院研究生院,北京,100049
2. 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明,650204
3. 贵阳医学院药学院,贵阳,550004
基金项目:国家自然科学基金,中国科学院基金 
摘    要:从云南美登木内生真菌Phomopsis species Lz42的琼脂平板发酵物中分离得到2个倍半萜和5个麦角甾醇类化合物(1~7), 其中化合物1和2为新化合物. 应用波谱技术确定其结构为4-Deacetyl-10-oxo-dihydrobotrydial(1)和麦角甾-6,22-二烯-5α,8α-环二氧-3-甲酸酯(2).

关 键 词:倍半萜  麦角甾醇类  Phomopsis  sp.  Lz42  内生真菌  云南美登木
收稿时间:2008-04-07

Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri
YUAN Lin,MA Juan,WANG Ting,LI Guo-Hong,SHEN Yue-Mao,ZHAO Pei-Ji.Chemical Constituents from Endophytic Phomopsis sp. Lz42 of Maytenus hookeri[J].Chemical Research In Chinese Universities,2009,30(1):78-81.
Authors:YUAN Lin  MA Juan  WANG Ting  LI Guo-Hong  SHEN Yue-Mao  ZHAO Pei-Ji
Institution:1. State Key Laboratory of Phytochemistry and Plant Resources in West China;Kunming Institute of Botany;Chinese Academy of Sciences;Kunming 650204;China;2. Graduate School of the Chinese Academy of Sciences;Beijing 100049;3.School of Pharmacy;Guiyang Medical University;Guiyang 550004;China
Abstract:Endophytes, commonly present in higher plants, are important sources of natural products with pharmaceutical potential. A new sesquiterpenoid, 4-deacetyl-10-oxo-dihydro-botrydial(1), and a new sterol, 22E,24R-5α,8α-epidioxyergosta-6,22-dien-3β-formate(2), were isolated from solid cultures of an endophytic fungal strain Phomopsis species Lz42, cultivated on Maytenus hookeri, together with five related known compounds, 4β-acetoxy-9β-10β-15α-trihydroxyprobotrydial(3), 22E,24R-5α,8α-epidioxyergosta-6,22-dien-3β-ol(4), ergosterol(5), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol(6) and 22E,24R-ergosta-7,22-diene-3β,5α,6β,9α-tetraol(7). Their structures were identified by extensive spectroscopic, experiments especially 2D-NMR.
Keywords:Phomopsis sp  Lz42
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